2021
PSEUDOURIDINE SYNTHASE 7 IS AN OPPORTUNISTIC ENZYME THAT BINDS AND MODIFIES SUBSTRATES WITH DIVERSE SEQUENCES AND STRUCTURES
MK Purchal, DE Eyler, M Tardu, MK Franco, MM Korn, T Khan, R McNassor, R Giles, K Lev, H Sharma, J Monroe, L Mallik, M Koutmos and KS Koutmou
PNAS, in press
2021
IN VITRO INVESTIGATION OF TRANSLATIONAL FIDELITY ON MODIFIED CODONS
Monroe JG, Smith TJ, Koutmou KS. Methods Enzymology (DOI: 10.1016/bs.mie.2021.06.011)
2021
COMMUNICATING SCIENCE TO THE GENERAL PUBLIC THROUGH A BIOCHEMISTRY WRITING ASSIGNMENT
Garza N, Finkenstaedt-Quinn S, Wilhelm, C, Koutmou K, Shultz G
Journal of Chemical Education (DOI: 10.1021/acs.jchemed.0c01176)
2020
A MOLECULAR LEVEL PERSPECTIVE ON THE FREQUENCY, DISTRIBUTION AND POSSIBLE CELLULAR ROLES OF MRNA MODIFICATIONS
JD Jones, J Monroe and KS Koutmou
WIREs RNA (DOI: 10.1002/wrna.1586)
2019
PSEUDOURIDINYLATION OF MRNA CODING SEQUENCES ALTERS TRANSLATION
DE Eyler, MK Franco, Z Batool, MZ Wu, ML Debuke, M Dobosz-Bartoszek, JD Jones, Y Polikanov, B Roy, KS Koutmou
PNAS (DOI: 10.1073/pnas.1821754116)
2019
IDENTIFICATION AND QUANTIFICATION OF MODIFIED NUCLEOSIDES IN SACCHAROMYCES CEREVISIAE MRNAS
M Tardu, JD Jones, RT Kennedy, Q Lin, KS Koutmou
ACS Chemical Biology (DOI: 10.1021/acschembio.9b00369)
2015
SYNTHESIS AT THE SPEED OF CODONS
KS Koutmou, A Radhakrishnan, R Green
Trends in Biomedical Sciences
2015
TRANSLATIONAL CONTROL BY LYSINE-ENCODING A-RICH SEQUENCES
L Arthur, S Pavlovic-Djuranovic, KS Koutmou, R Green, P Szczesny, S Djuranovic
Science Advances
2015
SID-1 EXTRACELLULAR DOMAIN SELECTIVELY BINDS LONG DSRNA AND IS REQUIRED FOR RNA TRANSPORT BY SID-1
W Li, KS Koutmou, DJ Leahy, M Li
Journal of Biological Chemistry
2015
RIBOSOMES SLIDE ON LYSINE-ENCODING HOMOPOLYMERIC A STRETCHES
KS Koutmou, AP Schuller, JL Brunelle, A Radhakrishnan, S Djuranovic, R Green
eLife
2014
RF3:GTP PROMOTES RAPID DISSOCIATION OF THE CLASS 1 TERMINATION FACTOR
KS Koutmou, ME McDonald, JL Brunelle, R Green
RNA
2011
THE RNR MOTIF OF B. SUBTILIS RNASE P PROTEIN INTERACTS WITH BOTH PRNA AND PRE-TRNA TO STABILIZE AN ACTIVE CONFORMER
KS Koutmou, JJ Day-Storms, CA Fierke
RNA
2010
A DIVALENT CATION STABILIZES THE ACTIVE CONFORMATION OF THE B. SUBTILIS RNASE P•PRE-TRNA COMPLEX: A ROLE FOR AN INNER-SPHERE METAL ION IN RNASE P
J Hsieh, KS Koutmou, D Rueda, M Koutmos, NG Walter, CA Fierke
Journal of Molecular Biology
2010
NMR AND XAS REVEAL AN INNER-SPHERE METAL BINDING SITE IN THE P4 HELIX OF THE METALLO-RIBOZYME RIBONUCLEASE P
KS Koutmou, A Casiano-Negroni, M Getz, S Paczini, AJ Andrews, JE Penner-Hahn, HM Al-Hashimi, CA Fierke
Proceedings of the National Academy of Sciences
2010
PROTEIN–PRECURSOR TRNA CONTACT LEADS TO SEQUENCE-SPECIFIC RECOGNITION OF 5′ LEADERS BY BACTERIAL RIBONUCLEASE P
KS Koutmou, NH Zahler, JC Kurz, FE Campbell, ME Harris, CA Fierke
Journal of Molecular Biology
2009
KINETIC MECHANISM OF BACTERIAL RNASE P
KS Koutmou, J Hsieh, CA Fierke
Protein Reviews, Volume 10: Ribonuclease P (book chapter)
2007
IMPORTANCE OF RNA-PROTEIN INTERACTIONS IN BACTERIAL RIBONUCLEASE P STRUCTURE AND CATALYSIS
JK Smith, J Hsieh, CA Fierke
Biopolymers