2021
METHYLATED GUANOSINE AND URIDINE MODIFICATIONS IN S. CEREVISIAE MRNAS MODULATE TRANSLATION
JD Jones, MK Franco, TJ Smith, LR Snyder, RT Kennedy, KS Koutmou
submitted
2021
CHEMICAL MODIFICATIONS TO MRNA NUCLEOBASES IMPACT TRANSLATION ELONGATION AND TERMINATION
MK Franco, KS Koutmou
submitted
2021
SEQUENCE AND MODIFICATION STATUS OF RNAS IN THE TRANSLATION MACHINERY DIRECT RIBOSOME MOVEMENTS DURING THE SYNTHESIS OF POLY(LYSINE) ENCODING PEPTIDES
TJ Smith, M Tardu, KS Koutmou
submitted
2021
SUPPORTING STUDENT LEARNING IN BIOCHEMISTRY USING A SCIENCE COMMUNICATION FOCUSED WRITING ASSIGNMENT
SA Finkenstaedt-Quinn, NF Garza, CA Wilhelm, KS Koutmou, GV Shultz
submitted
2021
THE CAMP SIGNALING PATHWAY REGULATES EPE1 PROTEIN LEVELS AND HETEROCHROMATIN ASSEMBLY
S Jia, K Bao, CM Shan, X Chen, G Raiymbek, JG Monroe, KS Koutmou, K Ragunathan, C Lu, L Berchowitz
under revision
2021
PSEUDOURIDINE SYNTHASE 7 IS AN OPPORTUNISTIC ENZYME THAT BINDS AND MODIFIES SUBSTRATES WITH DIVERSE SEQUENCES AND STRUCTURES
MK Purchal, DE Eyler, M Tardu, MK Franco, MM Korn, T Khan, R McNassor, R Giles, K Lev, H Sharma, J Monroe, L Mallik, M Koutmos, KS Koutmou
PNAS, in press
2021
IN VITRO INVESTIGATION OF TRANSLATIONAL FIDELITY ON MODIFIED CODONS
JG Monroe, TJ Smith, KS Koutmou
Methods Enzymology (DOI: 10.1016/bs.mie.2021.06.011)
2021
COMMUNICATING SCIENCE TO THE GENERAL PUBLIC THROUGH A BIOCHEMISTRY WRITING ASSIGNMENT
Garza N, Finkenstaedt-Quinn S, Wilhelm, C, Koutmou K, Shultz G
Journal of Chemical Education (DOI: 10.1021/acs.jchemed.0c01176)
2020
A MOLECULAR LEVEL PERSPECTIVE ON THE FREQUENCY, DISTRIBUTION AND POSSIBLE CELLULAR ROLES OF MRNA MODIFICATIONS
JD Jones, J Monroe and KS Koutmou
WIREs RNA (DOI: 10.1002/wrna.1586)
2019
PSEUDOURIDINYLATION OF MRNA CODING SEQUENCES ALTERS TRANSLATION
DE Eyler, MK Franco, Z Batool, MZ Wu, ML Debuke, M Dobosz-Bartoszek, JD Jones, Y Polikanov, B Roy, KS Koutmou
PNAS (DOI: 10.1073/pnas.1821754116)
2019
IDENTIFICATION AND QUANTIFICATION OF MODIFIED NUCLEOSIDES IN SACCHAROMYCES CEREVISIAE MRNAS
M Tardu, JD Jones, RT Kennedy, Q Lin, KS Koutmou
ACS Chemical Biology (DOI: 10.1021/acschembio.9b00369)
2015
SYNTHESIS AT THE SPEED OF CODONS
KS Koutmou, A Radhakrishnan, R Green
Trends in Biomedical Sciences
2015
TRANSLATIONAL CONTROL BY LYSINE-ENCODING A-RICH SEQUENCES
L Arthur, S Pavlovic-Djuranovic, KS Koutmou, R Green, P Szczesny, S Djuranovic
Science Advances
2015
SID-1 EXTRACELLULAR DOMAIN SELECTIVELY BINDS LONG DSRNA AND IS REQUIRED FOR RNA TRANSPORT BY SID-1
W Li, KS Koutmou, DJ Leahy, M Li
Journal of Biological Chemistry
2015
RIBOSOMES SLIDE ON LYSINE-ENCODING HOMOPOLYMERIC A STRETCHES
KS Koutmou, AP Schuller, JL Brunelle, A Radhakrishnan, S Djuranovic, R Green
eLife
2014
RF3:GTP PROMOTES RAPID DISSOCIATION OF THE CLASS 1 TERMINATION FACTOR
KS Koutmou, ME McDonald, JL Brunelle, R Green
RNA
2011
THE RNR MOTIF OF B. SUBTILIS RNASE P PROTEIN INTERACTS WITH BOTH PRNA AND PRE-TRNA TO STABILIZE AN ACTIVE CONFORMER
KS Koutmou, JJ Day-Storms, CA Fierke
RNA
2010
A DIVALENT CATION STABILIZES THE ACTIVE CONFORMATION OF THE B. SUBTILIS RNASE P•PRE-TRNA COMPLEX: A ROLE FOR AN INNER-SPHERE METAL ION IN RNASE P
J Hsieh, KS Koutmou, D Rueda, M Koutmos, NG Walter, CA Fierke
Journal of Molecular Biology
2010
NMR AND XAS REVEAL AN INNER-SPHERE METAL BINDING SITE IN THE P4 HELIX OF THE METALLO-RIBOZYME RIBONUCLEASE P
KS Koutmou, A Casiano-Negroni, M Getz, S Paczini, AJ Andrews, JE Penner-Hahn, HM Al-Hashimi, CA Fierke
Proceedings of the National Academy of Sciences
2010
PROTEIN–PRECURSOR TRNA CONTACT LEADS TO SEQUENCE-SPECIFIC RECOGNITION OF 5′ LEADERS BY BACTERIAL RIBONUCLEASE P
KS Koutmou, NH Zahler, JC Kurz, FE Campbell, ME Harris, CA Fierke
Journal of Molecular Biology
2009
KINETIC MECHANISM OF BACTERIAL RNASE P
KS Koutmou, J Hsieh, CA Fierke
Protein Reviews, Volume 10: Ribonuclease P (book chapter)
IMPORTANCE OF RNA-PROTEIN INTERACTIONS IN BACTERIAL RIBONUCLEASE P STRUCTURE AND CATALYSIS
2007
JK Smith, J Hsieh, CA Fierke
Biopolymers