Published Work
A molecular level perspective on the frequency, distribution and possible cellular roles of mRNA modifications
2020
JD Jones, J Monroe and KS Koutmou
WIREs RNA, in press
Pseudouridinylation of mRNA coding sequences alters translation
2019
DE Eyler, MK Franco, Z Batool, MZ Wu, ML Debuke, M Dobosz-Bartoszek, JD Jones, Y Polikanov, B Roy, KS Koutmou
PNAS (DOI: 10.1073/pnas.1821754116)
Identification and quantification of modified nucleosides in Saccharomyces cerevisiae mRNAs
2019
M Tardu, JD Jones, RT Kennedy, Q Lin, KS Koutmou
ACS Chemical Biology (DOI: 10.1021/acschembio.9b00369)
Synthesis at the speed of codons
2015
KS Koutmou, A Radhakrishnan, R Green
Trends in Biomedical Sciences
Translational control by lysine-encoding A-rich sequences
2015
L Arthur, S Pavlovic-Djuranovic, KS Koutmou, R Green, P Szczesny, S Djuranovic
Science Advances
SID-1 extracellular domain selectively binds long dsRNA and is required for RNA transport by SID-1
2015
W Li, KS Koutmou, DJ Leahy, M Li
Journal of Biological Chemistry
Ribosomes slide on lysine-encoding homopolymeric A stretches
2015
KS Koutmou, AP Schuller, JL Brunelle, A Radhakrishnan, S Djuranovic, R Green
eLife
RF3:GTP promotes rapid dissociation of the class 1 termination factor
2014
KS Koutmou, ME McDonald, JL Brunelle, R Green
RNA
The RNR motif of B. subtilis RNase P protein interacts with both PRNA and pre-tRNA to stabilize an active conformer
2011
KS Koutmou, JJ Day-Storms, CA Fierke
RNA
A divalent cation stabilizes the active conformation of the B. subtilis RNase P•pre-tRNA complex: a role for an inner-sphere metal ion in RNase P
2010
J Hsieh, KS Koutmou, D Rueda, M Koutmos, NG Walter, CA Fierke
Journal of Molecular Biology
NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P
2010
KS Koutmou, A Casiano-Negroni, M Getz, S Paczini, AJ Andrews, JE Penner-Hahn, HM Al-Hashimi, CA Fierke
Proceedings of the National Academy of Sciences
Protein–precursor tRNA contact leads to sequence-specific recognition of 5′ leaders by bacterial ribonuclease P
2010
KS Koutmou, NH Zahler, JC Kurz, FE Campbell, ME Harris, CA Fierke
Journal of Molecular Biology
Kinetic mechanism of bacterial RNase P
2009
KS Koutmou, J Hsieh, CA Fierke
Protein Reviews, Volume 10: Ribonuclease P (book chapter)
Importance of RNA-protein interactions in bacterial ribonuclease P structure and catalysis
2007
JK Smith, J Hsieh, CA Fierke
Biopolymers